Gene Symbol | USP49 |
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Entrez Gene | 25862 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 49 |
Other Description | deubiquitinating enzyme 49|ubiquitin carboxyl-terminal hydrolase 49|ubiquitin specific protease 49|ubiquitin thioesterase 49|ubiquitin thiolesterase 49|ubiquitin-specific-processing protease 49 |
Swissprots | Q5T3D9 Q5T3E0 Q96CK4 Q70CQ1 |
Accessions | EAX04065 Q70CQ1 AJ586139 CAE51939 AK023682 AL110255 BC014176 AAH14176 BU631853 DN992189 EF565089 JF432543 ADZ15760 NM_001286554 NP_001273483 NM_018561 NP_061031 |
Function | Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. {ECO:0000269|PubMed:23824326}. |
Subcellular Location | Nucleus {ECO:0000305|PubMed:23824326}. |
Human USP49 full length protein - ab161815 from Abcam
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Human USP49 protein fragment - ab161816 from Abcam
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USP49 Antibody Blocking Peptide - LS-E8053 from LifeSpan Bioscience
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Recombinant Human USP49 Protein - H00025862-P01 from Novus Biologicals
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USP49 Partial Recombinant Protein - H00025862-Q01 from Novus Biologicals
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USP49-Antibody-N-term-Blocking-peptide - BP5947a from Abgent, a WuXi AppTec company
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USP49 - H00025862-P01-10 from Acris Antibodies
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USP49 - H00025862-P01-25 from Acris Antibodies
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USP49 - H00025862-Q01-10 from Acris Antibodies
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USP49 - H00025862-Q01-25 from Acris Antibodies
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USP49 fusion protein - ag12697 from Proteintech Group
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Recombinant Human Ubiquitin carboxyl-terminal hydrolase 49(USP49) - CSB-YP761685HU CSB-EP761685HU CSB-BP761685HU CSB-MP761685HU from Cusabio
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USP49 Recombinant Protein Antigen - NBP1-81174PEP from Novus Biologicals
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USP49 Recombinant Protein Antigen - NBP1-81173PEP from Novus Biologicals
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USP49 Peptide, Human - M34GP17192H from Creative Peptides
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