SERPINE1

Gene Symbol	SERPINE1
Entrez Gene	5054
Alt Symbol	PAI, PAI-1, PAI1, PLANH1
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Other Description	endothelial plasminogen activator inhibitor|plasminogen activator inhibitor 1|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1|serpin E1
Swissprots	F8WD53 P05121 B7Z4S0
Accessions	AAA60007 AAA60009 AAD45828 AAK60338 CAA31722 CAA31729 CAB51606 CAB51607 CAB51639 CAB51737 CAB51738 CAB51739 CAY56481 CBX47312 EAW50195 EAW50196 EAW50197 P05121 AI752990 AK293248 BAH11475 AK297728 BAH12656 AK298048 BAH12712 AK316225 BAH14596 BC005927 BC010860 AAH10860 BC020765 BF351821 C00767 CN309001 CN309016 CN309038 DQ890694 ABM81620 DQ893877 ABM84803 M14083 AAA60008 M16006 AAA60003 X04429 CAA28025 X04729 CAA28438 X04731 CAA28442 X04744 CAA28444 X12701 CAA31208 NM_000602 NP_000593 NM_001165413
Function	Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. {ECO:0000269|PubMed:15853774}.
Subcellular Location	Secreted.
Tissue Specificity	Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.
Top Pathways	p53 signaling pathway, Complement and coagulation cascades, Chagas disease (American trypanosomiasis), Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAI1 (SERPINE1) Human ELISA Kit - ab108891 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 0.08 ng/ml Range 0.078 ng/ml - 5 ng/ml

PAI1 (SERPINE1) Human SimpleStep ELISA™ Kit - ab184863 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 21 pg/ml Range 94 pg/ml - 6000 pg/ml

PAI1 Human ELISA kit - ab157528 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 0.385 U/ml Range 0.125 U/ml - 100 U/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F2726 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 23-3000 pg/ml

Mouse SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F5572 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 13.4 pg/ml Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F5571 from LifeSpan Bioscience Category ELISA Kit Prices $520.00 Sizes 1 plate Sensitivity 4.6 pg/ml Range 23-3000 pg/ml

Rat SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F5573 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 23-3000 pg/ml

Rabbit SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F5390 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.29 ng/ml Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F467 from LifeSpan Bioscience Category ELISA Kit Prices $520.00, $930.00, $2,140.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.102 ng/ml Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F592 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 23-3000 pg/ml

Dog SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F10407 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.138 ng/ml Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F10421 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.037 ng/ml Range 23-3000 pg/ml

Mouse SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F10444 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.006 ng/ml Range 23-3000 pg/ml

Rat SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F10460 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 23-3000 pg/ml

Pig SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F10456 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.178 ng/ml Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10466 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.11 U/ml Range 23-3000 pg/ml

Dog SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10465 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Range 23-3000 pg/ml

Mouse SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10469 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.031 ng/ml Range 23-3000 pg/ml

Rat SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10476 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 0.079 ng/ml Range 23-3000 pg/ml

Rabbit SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10474 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Range 23-3000 pg/ml

Pig SERPINE1 / PAI-1 ELISA Kit (Functional ELISA) - LS-F10472 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Range 23-3000 pg/ml

Human SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F12251 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.156 Range 23-3000 pg/ml

Rat SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F12252 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.625 Range 23-3000 pg/ml

Mouse SERPINE1 / PAI-1 ELISA Kit (Sandwich ELISA) - LS-F12253 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 23-3000 pg/ml

Serpin E1/PAI-1 Colorimetric Assay Kit - KA0973 from Novus Biologicals Category Assay Kit Prices $659.00 Sizes 1 kit

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