SERPINE1

Gene Symbol	SERPINE1
Entrez Gene	5054
Alt Symbol	PAI, PAI-1, PAI1, PLANH1
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Other Description	endothelial plasminogen activator inhibitor|plasminogen activator inhibitor 1|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1|serpin E1
Swissprots	F8WD53 P05121 B7Z4S0
Accessions	AAA60007 AAA60009 AAD45828 AAK60338 CAA31722 CAA31729 CAB51606 CAB51607 CAB51639 CAB51737 CAB51738 CAB51739 CAY56481 CBX47312 EAW50195 EAW50196 EAW50197 P05121 AI752990 AK293248 BAH11475 AK297728 BAH12656 AK298048 BAH12712 AK316225 BAH14596 BC005927 BC010860 AAH10860 BC020765 BF351821 C00767 CN309001 CN309016 CN309038 DQ890694 ABM81620 DQ893877 ABM84803 M14083 AAA60008 M16006 AAA60003 X04429 CAA28025 X04729 CAA28438 X04731 CAA28442 X04744 CAA28444 X12701 CAA31208 NM_000602 NP_000593 NM_001165413
Function	Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. {ECO:0000269|PubMed:15853774}.
Subcellular Location	Secreted.
Tissue Specificity	Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.
Top Pathways	p53 signaling pathway, Complement and coagulation cascades, Chagas disease (American trypanosomiasis), Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SerpinE1 gene - orb90886 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-SERPINE1-cDNA-Clone - DC02998 from Abgent, a WuXi AppTec company Prices $542.70 Sizes 10 µg Species Human Accession BC010860

SERPINE1 - MBS1276990 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010860

Human SERPINE1 ORF Clone(NM_000602.4) - CDCL175121 from Creative Biomart Species Human Accession NM_000602.4

Human PAI-1 / SerpinE1 Gene ORF cDNA clone in cloning vector - HG10296-M from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10296-ACG from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10296-ACR from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10296-NH from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid - HG10296-UT from Sino Biological Species Human

Human SerpinE1 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10296-M-F from Sino Biological Species Human Accession NM_000602.3

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10296-CY from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10296-NF from Sino Biological Species Human

Human SerpinE1 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10296-M-N from Sino Biological Species Human Accession NM_000602.3

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10296-CF from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10296-NM from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10296-NY from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10296-CH from Sino Biological Species Human

Human PAI-1 / SerpinE1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10296-CM from Sino Biological Species Human

Human SERPINE1 ORF Clone (BC010860) - CDCS405785 from Creative biogene Species Human Accession P05121

Human SERPINE1 ORF clone (NM_000602.3) - CDCB157552 from Creative biogene Species Human

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