HRG

Gene Symbol	HRG
Entrez Gene	3273
Alt Symbol	HPRG, HRGP, THPH11
Species	Human
Gene Type	protein-coding
Description	histidine-rich glycoprotein
Other Description	histidine-proline-rich glycoprotein
Swissprots	B9EK35 P04196 D3DNU7
Accessions	BAA21613 CAA78925 EAW78183 EAW78184 P04196 AI800281 AK313381 BAG36179 BC069574 AAH69574 BC150591 AAI50592 CR749302 CAH18157 DA637240 M13149 AAA52694 XM_005247415 XP_005247472 NM_000412 NP_000403
Function	Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Binds heparin and heparin/glycosaminoglycans in a zinc-dependent manner. Binds heparan sulfate on the surface of liver, lung, kidney and heart endothelial cells. Binds to N-sulfated polysaccharide chains on the surface of liver endothelial cells. Inhibits rosette formation. Acts as an adapter protein and is implicated in regulating many processes such as immune complex and pathogen clearance, cell chemotaxis, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions. Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the
Subcellular Location	Secreted {ECO:0000269|PubMed:21215706}.
Tissue Specificity	Expressed in macrophages and in malignant cells. Expressed by the liver and secreted in plasma (at protein level). {ECO:0000269|PubMed:14744774, ECO:0000269|PubMed:19903770, ECO:0000269|PubMed:21215706}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse HRG ELISA Kit (Sandwich ELISA) - LS-F6589 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 1.38 ng/ml Range 0.469-30 ng/ml

Human HRG ELISA Kit (Sandwich ELISA) - LS-F7563 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.21 ng/ml Range 0.469-30 ng/ml

Rat HRG ELISA Kit (Sandwich ELISA) - LS-F9061 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 0.469-30 ng/ml

Human HRG ELISA Kit (Sandwich ELISA) - LS-F11662 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 0.469-30 ng/ml

Human HRGP ELISA Kit - abx054214 from Abbexa Category ELISA Kit

Histidine Rich Glycoprotein (HRG), Human, ELISA Kit - SEC534Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 6.8pg/mL Range 15.6-1,000pg/mL

Histidine-rich glycoprotein (HRG), Human, ELISA Kit - CSB-E13159h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.56 ?g/ml Range 6.25 ?g/ml-400 ?g/ml

HRG (Human) IP-WB Antibody Pair - H00003273-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Custom Human HPRG ELISA - ELH-HPRG from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human HRGP ELISA Kit - HH0282 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine HRGP ELISA Kit - AH0282 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Histidine Rich Glycoprotein (HRG), ELISA Kit - MBS2022198 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.21ng/mL. Range 0.469-30ng/mL

Histidine Rich Glycoprotein (HRG), ELISA Kit - MBS2019391 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 1.38ng/mL. Range 3.13-200ng/mL

Histidine Rich Glycoprotein (HRG), ELISA Kit - MBS2022386 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat HRG is typically less than 0.069ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS2601757 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS260383 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS261153 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS266285 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS263011 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.6 ng/ml. Range 200 ng/ml-3.12 ng/ml

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS266094 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS265417 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5 pg/ml. Range 1000 pg/ml-15.6 pg/ml

Histidine Rich Glycoprotein (HRGP), ELISA Kit - MBS265189 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.6 ng/ml. Range 200 ng/ml-3.12 ng/ml

Histidine-proline-rich glycoprotein (HPRG), ELISA Kit - MBS9305606 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine-proline-rich glycoprotein (HPRG), ELISA Kit - MBS9305609 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histidine-proline-rich glycoprotein (HPRG), ELISA Kit - MBS9305130 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0ng/ml. Range 3.12 ng/ml - 100 ng/ml.

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