HEXIM1

Gene Symbol	HEXIM1
Entrez Gene	10614
Alt Symbol	CLP1, EDG1, HIS1, MAQ1
Species	Human
Gene Type	protein-coding
Description	hexamethylene bis-acetamide inducible 1
Other Description	HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1|protein HEXIM1
Swissprots	O94992 B2R8Y5
Accessions	O94992 AB021179 BAA36166 AI092623 AK023624 BAG51211 AK313557 BAG36332 AL521530 AL562001 AW881781 BC006460 AAH06460 BQ777682 BX111838 CA448958 CA946973 CV810471 DB539383 DQ893272 ABM84198 DQ896158 ABM87157 DQ896603 ABM87602 NM_006460 NP_006451
Function	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:14580347, ECO:0000269|PubMed:15201869, ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15940264, ECO:0000269|PubMed:15941832, ECO:0000269|PubMed:17088550}.
Subcellular Location	Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear.
Tissue Specificity	Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HEXIM1-Over-expression-Lysate - LY14834a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

HEXIM1 293T Cell Transient Overexpression Lysate(Denatured) - H00010614-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HIS1 293T Cell Transient Overexpression Lysate(Denatured) - H00010614-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HEXIM1 293 Cell Lysate - 407773 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Hexim 1 Overexpression Lysate (Denatured) - H00010614-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

Hexim 1 Overexpression Lysate (Native) - NBL1-11518 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

HEXIM1 (h2): 293T Lysate - sc-171805 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HEXIM1 Over-expression Lysate Product - GWB-85001D from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Hexim 1 Overexpression Lysate (Denatured) - H00010614-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human HEXIM1 Knockdown Stable Cell Line - CSC-DC006959 from Creative biogene Category Cell Line Species Human

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