HEXIM1

Gene Symbol HEXIM1
Entrez Gene 10614
Alt Symbol CLP1, EDG1, HIS1, MAQ1
Species Human
Gene Type protein-coding
Description hexamethylene bis-acetamide inducible 1
Other Description HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1|protein HEXIM1
Swissprots O94992 B2R8Y5
Accessions O94992 AB021179 BAA36166 AI092623 AK023624 BAG51211 AK313557 BAG36332 AL521530 AL562001 AW881781 BC006460 AAH06460 BQ777682 BX111838 CA448958 CA946973 CV810471 DB539383 DQ893272 ABM84198 DQ896158 ABM87157 DQ896603 ABM87602 NM_006460 NP_006451
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:14580347, ECO:0000269|PubMed:15201869, ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15940264, ECO:0000269|PubMed:15941832, ECO:0000269|PubMed:17088550}.
Subcellular Location Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear.
Tissue Specificity Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}.

HEXIM1 Antibody - 9064 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using HEXIM1 Antibody.

HEXIM1 (D5Y5K) Rabbit mAb - 12604 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5Y5K
Western blot analysis of extracts from various cell lines using HEXIM1 (D5Y5K) Rabbit mAb

HEXIM1 (E-7) - sc-365413 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HEXIM1 (E-7): sc-365413. Western blot analysis of HEXIM1 expression in SK-N-MC whole cell lysate.

HEXIM1 (C-12) - sc-48870 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HEXIM1 (G-10) - sc-398479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HEXIM1 (G-10): sc-398479. Western blot analysis of HEXIM1 expression in HeLa (A), K-562 (B) and Jurkat (C) whole cell lysates.

HEXIM1 (N-13) - sc-48871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HEXIM1 (N-13): sc-48871. Western blot analysis of HEXIM1 expression in Sol8 (A) and SK-N-MC (B) whole cell lysates.

HEXIM1 (Q-20) - sc-48872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HEXIM1 (Q-20): sc-48872. Western blot analysis of HEXIM1 expression in HeLa whole cell lysate.

HEXIM1 (H-66) - sc-134786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HEXIM1 (H-66): sc-134786. Western blot analysis of HEXIM1 expression in K-562 whole cell lysate.

HEXIM1 (S-19) - sc-48873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HEXIM1 (S-19): sc-48873. Western blot analysis of HEXIM2 expression in HeLa whole cell lysate.

HEXIM1 (D-8) - sc-390059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HEXIM1 (D-8): sc-390059. Western blot analysis of HEXIM1 expression in SK-N-MC (A) and Sol8 (B) whole cell lysates.

HEXIM1 (2416C2a) - sc-81285 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HEXIM1 (2416C2a): sc-81285 Western Blot analysis of human recombinant HEXIM1 fusion protein.

Anti-HEXIM1 antibody - ab28016 from Abcam

Prices $382.00
Sizes 200 µl
Host Sheep
Clonality Polyclonal
All lanes : Anti-HEXIM1 antibody (ab28016) at 1/1000 dilutionLane 1 : recombinant 6x His tagged HEXIM1 proteinLane 2 : Hela whole cell lysateLane 3 : Hela cell nuclear lysateSecondarydonkey anti-sheep peroxidase conjugate at 1/20000 dilution

Anti-HEXIM1 antibody - ab58573 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-HEXIM1 antibody (ab58573) at 0.3 µg/ml + Human Heart lysate at 35 µg

Anti-HEXIM1 antibody - ab136818 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HEXIM1 antibody (ab136818) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-HEXIM1 antibody - ab112094 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Staining of HEXIM1 in HeLa whole cell lysate immunoprecipitated using ab112094 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: controle IgG.

Anti-HEXIM1 antibody - ab172495 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-HEXIM1 antibody (ab172495) at 1/500 dilutionLane 1 : HEXIM1-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-HEXIM1 antibody [2416C2a] - ab58624 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2416C2a
Anti-HEXIM1 antibody [2416C2a] (ab58624) + immunogen (recombinant pfragment)

Anti-HEXIM1 antibody - ChIP Grade - ab25388 from Abcam

Prices $403.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HEXIM1 antibody - ChIP Grade (ab25388) at 1/250 dilutionLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 5 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution

Anti-HEXIM1 Antibody (aa346-359) - LS-C54964 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of 1) HeLa cell lysate and 2) recombinant HEXIM1 (3ng). Detected by chemiluminescence. Data kindly provided by David Price and Jeff Cooper, University of Iowa, USA.

Anti-HEXIM1 Antibody (aa201-230, AP) - LS-C236186 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEXIM1 Antibody (clone 2416C2a) - LS-C184581 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2416C2a
Western blot of immunized recombinant protein using HEXIM1 antibody.

Anti-HEXIM1 Antibody (aa201-230, APC) - LS-C236187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEXIM1 Antibody (clone 4G4) - LS-C134025 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G4
Immunoperoxidase of monoclonal antibody to HEXIM1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 1.5 ug/ml]

Anti-HEXIM1 Antibody (aa201-230, Biotin) - LS-C236188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEXIM1 Antibody (aa201-230, PE) - LS-C236190 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more