HEXIM1

Gene Symbol	HEXIM1
Entrez Gene	10614
Alt Symbol	CLP1, EDG1, HIS1, MAQ1
Species	Human
Gene Type	protein-coding
Description	hexamethylene bis-acetamide inducible 1
Other Description	HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1|protein HEXIM1
Swissprots	O94992 B2R8Y5
Accessions	O94992 AB021179 BAA36166 AI092623 AK023624 BAG51211 AK313557 BAG36332 AL521530 AL562001 AW881781 BC006460 AAH06460 BQ777682 BX111838 CA448958 CA946973 CV810471 DB539383 DQ893272 ABM84198 DQ896158 ABM87157 DQ896603 ABM87602 NM_006460 NP_006451
Function	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:14580347, ECO:0000269|PubMed:15201869, ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15940264, ECO:0000269|PubMed:15941832, ECO:0000269|PubMed:17088550}.
Subcellular Location	Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear.
Tissue Specificity	Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-HEXIM1-cDNA-Clone - DC01982 from Abgent, a WuXi AppTec company Prices $484.65 Sizes 10 µg Species Human Accession BC006460

HEXIM1 - MBS1271655 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC006460

Human HEXIM1 cDNA clone(NM_006460.2) - CDFH008430 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 cDNA clone(NM_006460.2) - CDFH008431 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 ORF Clone(NM_006460.2) - CDCR292946 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 ORF Clone(NM_006460.2) - CDCR292947 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 ORF Clone(NM_006460.2) - CDCR292948 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 ORF Clone(NM_006460.2) - CDCL165973 from Creative Biomart Species Human Accession NM_006460.2

Human HEXIM1 Gene ORF cDNA clone in cloning vector - HG14736-U from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid - HG14736-UT from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14736-CY from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14736-ACR from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14736-ANR from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14736-NY from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14736-ACG from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14736-NF from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14736-NH from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14736-CF from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14736-CH from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14736-NM from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14736-CM from Sino Biological Species Human

Human HEXIM1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14736-ANG from Sino Biological Species Human

Human HEXIM1 ORF Clone(NM_006460.2) - CDCR292946 from Creative biogene Species Human

Human HEXIM1 ORF Clone (BC006460) - CDCS412753 from Creative biogene Species Human Accession O94992

Human HEXIM1 ORF clone (BC006460) - CDCB158590 from Creative biogene Species Human

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