HEXIM1

Gene Symbol	HEXIM1
Entrez Gene	10614
Alt Symbol	CLP1, EDG1, HIS1, MAQ1
Species	Human
Gene Type	protein-coding
Description	hexamethylene bis-acetamide inducible 1
Other Description	HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1|protein HEXIM1
Swissprots	O94992 B2R8Y5
Accessions	O94992 AB021179 BAA36166 AI092623 AK023624 BAG51211 AK313557 BAG36332 AL521530 AL562001 AW881781 BC006460 AAH06460 BQ777682 BX111838 CA448958 CA946973 CV810471 DB539383 DQ893272 ABM84198 DQ896158 ABM87157 DQ896603 ABM87602 NM_006460 NP_006451
Function	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:14580347, ECO:0000269|PubMed:15201869, ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15940264, ECO:0000269|PubMed:15941832, ECO:0000269|PubMed:17088550}.
Subcellular Location	Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear.
Tissue Specificity	Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HEXIM1 full length protein - ab117163 from Abcam Category Protein Source E. coli Species Human

Human HEXIM1 peptide - ab26978 from Abcam Category Peptide

HEXIM1 Antibody Blocking Peptide - LS-E1121 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HEXIM1 Antibody Blocking Peptide - LS-E2869 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HEXIM1 Antibody Blocking Peptide - LS-E12198 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HEXIM1 Antibody Blocking Peptide - LS-E25967 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Hexim 1 Protein - NBP1-37094 from Novus Biologicals Category Protein Prices $499.00 Sizes 100 µg Source E. coli Species Human

Hexim 1 Recombinant Protein - H00010614-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HEXIM1-antibody-Center-Blocking-peptide - BP11642c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HEXIM1-Antibody-N-term-Blocking-peptide - BP13992a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HEXIM1 blocking peptide - GTX89214-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

HEXIM1 Protein (OPPA02107) - OPPA02107 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Hexamethylene Bis-Acetamide Inducible 1 protein - orb81156 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Goat anti HEXIM1 antibody Immunizing peptide - orb17583 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

HEXIM1 Peptide - AC21-0794-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HEXIM1 (1-359, His-tag) - AR09374PU-L from Acris Antibodies Category Protein Prices $1,470.00 Sizes 500 µg Source E. coli Species Human

HEXIM1 (1-359, His-tag) - AR09374PU-N from Acris Antibodies Category Protein Prices $570.00 Sizes 100 µg Source E. coli Species Human

HEXIM1 - H00010614-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HEXIM1 - H00010614-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Hexamethylene Bis-Acetamide Inducible 1, Human Recombinant - 228-13232-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Hexamethylene Bis-Acetamide Inducible 1 - 228-13232-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Hexamethylene Bis-Acetamide Inducible 1 - 228-13232-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

HEXIM1, 1-359aa, Human, His tag, E.coli - 01-1779-1 from ARP American Research Products Category Protein Prices $229.00, $230.00, $609.00 Sizes 20 µg, 500 µg, 100 µg Species Human

HEXIM1 Peptide - 45-727P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

HEXIM1 fusion protein - Ag8019 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

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