HEXIM1

Gene Symbol HEXIM1
Entrez Gene 10614
Alt Symbol CLP1, EDG1, HIS1, MAQ1
Species Human
Gene Type protein-coding
Description hexamethylene bis-acetamide inducible 1
Other Description HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1|protein HEXIM1
Swissprots O94992 B2R8Y5
Accessions O94992 AB021179 BAA36166 AI092623 AK023624 BAG51211 AK313557 BAG36332 AL521530 AL562001 AW881781 BC006460 AAH06460 BQ777682 BX111838 CA448958 CA946973 CV810471 DB539383 DQ893272 ABM84198 DQ896158 ABM87157 DQ896603 ABM87602 NM_006460 NP_006451
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:14580347, ECO:0000269|PubMed:15201869, ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15940264, ECO:0000269|PubMed:15941832, ECO:0000269|PubMed:17088550}.
Subcellular Location Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear.
Tissue Specificity Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}.

HEXIM1 CRISPR/Cas9 KO Plasmid (h) - sc-402333 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 HDR Plasmid (h) - sc-402333-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 Double Nickase Plasmid (h) - sc-402333-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 Double Nickase Plasmid (h2) - sc-402333-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 CRISPR Activation Plasmid (h) - sc-402333-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 CRISPR Activation Plasmid (h2) - sc-402333-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 Lentiviral Activation Particles (h) - sc-402333-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 Lentiviral Activation Particles (h2) - sc-402333-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HEXIM1 siRNA (h) - sc-60787 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HEXIM1 shRNA Plasmid (h) - sc-60787-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HEXIM1 shRNA (h) Lentiviral Particles - sc-60787-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU130571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10003 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10003 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10389 from Sigma-Aldrich

Category miRNA

HEXIM1 siRNA (Human) - CRH7227 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Hexim 1 RNAi - H00010614-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

HEXIM1 - MBS8213121 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HEXIM1 (NM_006460.2) - SHH311801 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HEXIM1(NM_006460.2) - SHG183889 from Creative biogene

Category siRNA
Species Reactivities Human

HEXIM1 shRNA Plasmid (Human) - CHH7227 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HEXIM1 miRNA 3'UTR clone - MiUTR1H-04470 from Creative biogene

Species Reactivities Human
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