SEMA4C

Gene Symbol SEMA4C
Entrez Gene 54910
Alt Symbol M-SEMA-F, SEMACL1, SEMAF, SEMAI
Species Human
Gene Type protein-coding
Description sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Other Description M-Sema F|semaphorin-4C
Swissprots Q32MJ3 Q9C0C4 Q7Z5X0
Accessions AAY14967 EAW71325 EAW71326 EAW71327 Q9C0C4 AB051526 BAB21830 AF258577 AAG23780 AF370374 AAQ15210 AK000376 BAA91124 AK075388 BAC11588 AK126512 BAG54340 AY358842 AAQ89201 BC017476 AAH17476 BC062984 AAH62984 BC109103 AAI09104 BC109104 AAI09105 BI518922 XM_006712606 XP_006712669 XM_011511378 XP_011509680 XM_011511379 XP_011509681 XM_011511380 XP_011509682 XM_011511381 XP_011509683 XM_011511382 XP_011509684 XM_011511383 XP_011509685 NM_017789 NP_060259
Function Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. {ECO:0000250, ECO:0000269|PubMed:17498836}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways Axon guidance

SEMA4C (37) - sc-136445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SEMA4C (37): sc-136445. Western blot analysis of SEMA4C expression in SW13 whole cell lysate.

SEMA4C (C-14) - sc-169282 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SEMA4C (C-14): sc-169282. Western blot analysis of SEMA4C expression in PC-12 (A), SW-13 (B), K-562 (C) and MCF7 (D) whole cell lysates.

SEMA4C (N-16) - sc-169284 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SEMA4C (N-16): sc-169284. Western blot analysis of SEMA4C expression in PC-12 whole cell lysate.

Anti-SEMA4C antibody - ab197088 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-SEMA4C antibody (ab197088) at 1/500 dilution + K562 lysate

Anti-SEMA4C antibody - ab135856 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SEMA4C antibody (ab135856) at 1/500 dilution + SW13 cell extract at 30 µg

Anti-SEMA4C antibody - ab121334 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121334, at 1/225, staining SEMA4C in paraffin embedded Human small intestine tissue by Immunohistochemistry.

Anti-SEMA4C antibody - C-terminal - ab171559 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SEMA4C antibody - C-terminal (ab171559) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-SEMA4C / Semaphorin 4C Antibody (aa21-663) - LS-C150056 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal
Semaphorin 4C in Human Brain. Semaphorin 4C was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Sheep Anti-Human Semaphorin 4C Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained using Anti-Sheep HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies.

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821) - LS-C168955 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SEMA4C Antibody western blot of K562 cell line lysates (35 ug/lane). The SEMA4C antibody detected the SEMA4C protein (arrow).

Anti-SEMA4C / Semaphorin 4C Antibody (aa22-664) - LS-C150248 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal
Semaphorin 4C in Mouse Embryo. Semaphorin 4C was detected in perfusion fixed frozen sections of mouse embryo (13 d. p. c.) using Sheep Anti-Mouse Semaphorin 4C Antigen Affinity-purified Polyclonal Antibody at 1.7 ug/ml overnight at 4°C. Tissue was stained using Anti-Sheep HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal processes of the developing cerebellum.

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, AP) - LS-C217438 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, Biotin) - LS-C217440 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, APC) - LS-C217439 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, FITC) - LS-C217441 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, Azide-free, HRP) - LS-C217442 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa792-821, PE) - LS-C217443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C Antibody (aa791-821) - LS-C324993 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEMA4C / Semaphorin 4C Antibody (aa309-358) - LS-C200001 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from SW13 cells, using SEMA4C antibody.

Semaphorin 4C Antibody [Unconjugated] - AF6120 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of mouse embryo (15 d.p.c.) tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Mouse/Rat Semaphorin 4C Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6120) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Semaphorin 4C at approximately 240 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.

Semaphorin 4C Antibody [Unconjugated] - AF6125 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of SW13 human adrenal cortex adenocarcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human Semaphorin 4C Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6125) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Semaphorin 4C at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Semaphorin 4C Antibody (660016) - MAB6125 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 660016
Western blot shows lysates of MCF‑7 human breast cancer cell line. PVDF Membrane was probed with 2 µg/mL of Human Semaphorin 4C Monoclonal Antibody (Catalog # MAB6125) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Semaphorin 4C at approximately 100 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.

Semaphorin 4C Antibody - NBP1-80769 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Semaphorin 4C Antibody [NBP1-80769] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Anti-SEMA4C antibody produced in rabbit - HPA011090 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEMA4C: <B>Cat. No. HPA011090</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach tissue showing cytoplasmic and/or membranous staining of glandular cells.

ANTI-SEMA4C (C-TERM) antibody produced in rabbit - SAB1304563 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SEMA4C (C-term): <B>Cat. No. SAB1304563</B>: SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35 μg/lane).

SEMA4C-Antibody-C-term - AP13003b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SEMA4C Antibody (C-term) (Cat. #AP13003b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).
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