MDK

Gene Symbol	MDK
Entrez Gene	4192
Alt Symbol	ARAP, MK, NEGF2
Species	Human
Gene Type	protein-coding
Description	midkine (neurite growth-promoting factor 2)
Other Description	amphiregulin-associated protein|midgestation and kidney protein|midkine|neurite outgrowth-promoting factor 2|retinoic acid inducible factor
Swissprots	Q2LEK4 P21741 Q9UCC7
Accessions	AAA59850 BAA01457 CCD35255 EAW68005 P21741 AI494596 AK130889 AK308210 AK309963 BC011704 AAH11704 BF684205 BI915189 BM016739 BM761575 BM887813 BX346163 CN266354 CN266369 CN266376 DQ323888 ABC55425 DQ323889 ABC55426 DQ323890 ABC55427 DQ893220 ABM84146 DQ896549 ABM87548 M69148 AAA58478 X55110 CAA38908 XM_011520116 XP_011518418 NM_001012333 NP_001012333 NM_001012334 NP_001012334 NM_001270550 NP_001257479 NM_001270551 NP_001257480 NM_001270552 NP_001257481 NM_002391 NP_002382 NR_073039
Function	Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity). {ECO:0000250}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions. {ECO:0000269|PubMed:17379400}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Midkine Human SimpleStep ELISA™ Kit - ab193761 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 3.5 pg/ml Range 15.6 pg/ml - 1000 pg/ml

Human MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F2908 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 32-2000 pg/ml

Human MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F4369 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.056 ng/ml Range 32-2000 pg/ml

Mouse MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F5765 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 32-2000 pg/ml

Human MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F589 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 32-2000 pg/ml

Rat MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F7818 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 7.2 pg/ml Range 32-2000 pg/ml

Mouse MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F12048 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 32-2000 pg/ml

Human MDK / Midkine ELISA Kit (Sandwich ELISA) - LS-F12049 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 32-2000 pg/ml

Human Midkine DuoSet ELISA - DY258 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 78.10 - 5,000 pg/mL

Midkine ELISA Kit (Human) : 96 Wells (OKAG00050) - OKAG00050 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 32 pg/mL Range 32-2,000 pg/mL

Human Midkine ELISA Kit - abx056270 from Abbexa Category ELISA Kit

Human Midkine ELISA Kit - abx051395 from Abbexa Category ELISA Kit

Human Midkine ELISA Kit - abx152333 from Abbexa Category ELISA Kit Sensitivity 0.133 ng/ml Range 0.313 ng/ml - 20 ng/ml

Midkine (MK), Human, ELISA Kit - SEA631Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.127ng/mL Range 0.312-20ng/mL

Midkine, Human, ELISA Kit - E01M0292 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Midkine, MDK, Human, ELISA Kit - E0631h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

Midkine, MK, Human, ELISA Kit - E-EL-H2297 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Midkine, MK, Rabbit, ELISA Kit - E-EL-RB1547 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Midkine, MK, Chicken, ELISA Kit - E-EL-Ch0741 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Midkine, MK, Porcine, ELISA Kit - E-EL-P0621 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Midkine, MK, Sheep, ELISA Kit - E-EL-S0603 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Midkine, MK, Guinea Pig, ELISA Kit - E-EL-GP0664 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Midkine, MK, Monkey, ELISA Kit - E-EL-MK0845 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

MDK (Human) IP-WB Antibody Pair - H00004192-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Human MDK ELISA - ELH-MDK from RayBiotech Category ELISA Kit Prices $462.00, $832.00, $1,850.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 0.12 ng/ml Range 0.12 ng/ml - 30 ng/ml

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