ELK4

Gene Symbol ELK4
Entrez Gene 2005
Alt Symbol SAP1
Species Human
Gene Type protein-coding
Description ELK4, ETS-domain protein (SRF accessory protein 1)
Other Description ETS domain-containing protein Elk-4|SAP-1|serum response factor accessory protein 1
Swissprots P28324 P28323 Q6GSJ2
Accessions CCV01469 CCV01470 EAW91570 EAW91571 EAW91572 EAW91573 EAW91574 P28324 AF075044 AI002107 AI005122 AK024944 AL117645 BC040145 AAH40145 BC063676 AAH63676 BE041598 BE675475 BE676052 BF433322 BX346360 EU446469 ABZ91998 M85164 AAA03632 M85165 AAA03631 T27937 XM_005244950 XP_005245007 XM_005244951 XP_005245008 XR_426764 XR_426766 XR_921752 XR_921753 NM_001973 NP_001964 NM_021795 NP_068567
Function Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously. {ECO:0000269|PubMed:22722849}.
Subcellular Location Nucleus.
Top Pathways MAPK signaling pathway, HTLV-I infection, Transcriptional misregulation in cancer

SAP-1a (H-3) - sc-166823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SAP-1a (H-3): sc-166823. Western blot analysis of SAP-1a expression in SK-N-MC (A) and Jurkat (B) whole cell lysates.

SAP-1a (C-20) - sc-1426 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SAP-1a (H-167) - sc-13030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SAP-1a (H-167): sc-13030. Western blot analysis of SAP-1a expression in SK-N-MC whole cell lysate.

Anti-ELK4 antibody - ab33075 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ELK4 antibody (ab33075) at 2.5 µg/ml + Jurkat cell lysate at 10 µg with 5% skimmed milk in PBSSecondaryHRP conjugated anti-Rabbit IgG diluted in 1: 50,000 - 100,000

Anti-ELK4 antibody - ab86002 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ELK4 antibody (ab86002) at 1/1000 dilution (in 5% non-fat milk-PBST solution incubated for 60 minutes)Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution) Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution) Secondaryanti-Rabbit IgG HRP conjugated incubated for 60 minutes at 1/1000 dilution

Anti-ELK4 antibody - ab49244 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ELK4 antibody (ab49244) at 2.5 µg/ml + Jurkat cell lysate at 10 µg with 5% skim milk in PBS.SecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ELK4 antibody - ab43741 from Abcam

Prices $359.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-ELK4 antibody (ab43741) at 1/1000 dilutionLane 1 : a total protein extract from E coli with 50ng to 100 ng of a GST fusion protein of an irrelevant antigenLane 2 : a total protein extract from E coli with 50ng to 500ng of the antigen (GST-antigen fusion protein)Lysates/proteins at 20 µg per lane.SecondaryRabbit anti-mouse IgG + IgM, (H+L) conjugated to Horseradish peroxidase at 1/5000 dilution

Anti-ELK4 Antibody - LS-C307386 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ELK4 Antibody - LS-C310243 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELK4 Antibody (C-Terminus) - LS-C31028 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-ELK4 Antibody (C-Terminus) - LS-C134927 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELK4 antibody LS-C134927 Western blot of 721_B cell lysate.

Anti-ELK4 Antibody (C-Terminus) - LS-C82062 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ELK4 Antibody (aa108-157) - LS-C109920 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELK4 antibody LS-C109920 Western blot of Fetal Liver lysate.

Anti-ELK4 Antibody (clone 3D1) - LS-C197130 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D1
Detection limit for recombinant GST tagged ELK4 is 3 ng/ml as a capture antibody.

ELK4 Antibody - NBP1-87092 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELK4 Antibody [NBP1-87092] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY411912)

ELK4 Antibody - H00002005-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ELK4 Antibody - NBP1-69129 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELK4 Antibody [NBP1-69129] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

ELK4 Antibody - H00002005-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ELK4 Antibody [H00002005-D01P] - Analysis of ELK4 expression in transfected 293T cell line by ELK4 polyclonal antibody.Lane 1: ELK4 transfected lysate(44.70 KDa).Lane 2: Non-transfected lysate.

ELK4 Antibody (3D1) - H00002005-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D1
Sandwich ELISA: ELK4 Antibody (3D1) [H00002005-M02] - Detection limit for recombinant GST tagged ELK4 is 3 ng/ml as a capture antibody.

ELK4/SAP-1a Polyclonal Antibody - bs-13067R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELK4/SAP-1a Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13067R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELK4/SAP-1a Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13067R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELK4/SAP-1a Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13067R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELK4/SAP-1a Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13067R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELK4/SAP-1a Polyclonal Antibody, Cy3 Conjugated - bs-13067R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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