CUL4A

Gene Symbol CUL4A
Entrez Gene 8451
Alt Symbol -
Species Human
Gene Type protein-coding
Description cullin 4A
Other Description CUL-4A|cullin-4A
Swissprots Q9UP17 O75834 Q13619 Q6UP08 A2A2W2 Q589T6 Q5TC62
Accessions EAX09201 Q13619 AB012193 BAA33146 AB178950 BAD93235 AF077188 AAD45191 AK126278 AK296700 BAG59294 AK314835 BAG37354 AL833355 AY365124 AAR13072 BC008308 AAH08308 BC015166 BM835927 BX439434 CA445237 DA478924 DA574202 DB455959 EU176793 ABW03594 U58090 AAC50547 XM_011537523 XP_011535825 XM_011537524 XP_011535826 NM_001008895 NP_001008895 NM_001278513 NP_001265442 NM_001278514 NP_001265443 NM_003589 NP_003580
Function Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX(DET1-COP1) directs ubiquitination of JUN. DCX(DDB2) directs ubiquitination of XPC. DCX(DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3.1) and replication-independent (H3.3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition. DCX(DTL) plays a role in PCNA-dep
Top Pathways Ubiquitin mediated proteolysis, Nucleotide excision repair

Rabbit anti-Cul4a Antibody, Affinity Purified - PLA0136 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-Cul4a Antibody, Affinity Purified: <B>Cat. No. PLA0136</B>: Detection of Human and Mouse Cul4a by Immunohistochemistry. Sample: FFPE section of Human breast carcinoma (left) and Mouse squamous cell carcinoma (right). Antibody: Affinity purified Rabbit Anti-Cul4a (<B>Cat. No. PLA0136</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

Cullin-4A (CUL4A), Human, ELISA Kit - E01C2184 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 2.5-50ng/ml

Cullin 4A (CUL4A), ELISA Kit - MBS9313050 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin 4A (CUL4A), ELISA Kit - MBS7237843 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Cullin-4A (CUL4A), ELISA Kit - MBS7230740 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7236889 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7242266 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7245854 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7244896 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7251594 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7249861 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7221192 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7228125 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7233001 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-4A (CUL4A), ELISA Kit - MBS7225082 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CUL4A ELISA Kit - E010384 from Biobool

Category ELISA Kit
Sensitivity 0.1 ng/mL.
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