CCL14

Gene Symbol	CCL14
Entrez Gene	6358
Alt Symbol	CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 14
Other Description	C-C motif chemokine 14|chemokine CC-1/CC-3|chemokine CC-3|hemofiltrate CC chemokine 1|new CC chemokine 2|small inducible cytokine subfamily A (Cys-Cys), member 14|small-inducible cytokine A14
Swissprots	Q16627 E1P649 Q13954 E1P650
Accessions	AAC63329 AAF23982 CAA89263 EAW80105 EAW80106 EAW80107 EAW80108 Q16627 AA612866 AK122606 BC038289 AAH38289 BC045165 AAH45165 BC050647 BI496964 BM853193 DA821276 HQ257907 ADR82662 Z49270 CAA89264 NM_032962 NP_116738 NM_032963 NP_116739 NM_004166
Function	Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:11085751}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations (1-80 nM) in plasma. {ECO:0000269|PubMed:9600961}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CCL14 full length protein - ab195087 from Abcam Category Protein Prices $176.00 Sizes 4 µg Source Mammalian Species Human

Active human CCL14 full length protein - ab69500 from Abcam Category Protein Prices $110.00, $239.00 Sizes 2 µg, 10 µg Source E. coli Species Human

Active human CCL14 full length protein - ab192124 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Active human CCL14 full length protein - ab73836 from Abcam Category Protein Prices $239.00 Sizes 10 µg Source E. coli Species Human

Human CCL14 full length protein - ab151939 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CCL14 full length protein - ab104678 from Abcam Category Protein Prices $235.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human CCL14 full length protein - ab195067 from Abcam Category Protein Prices $176.00 Sizes 4 µg Source Mammalian Species Human

Recombinant Human CCL14/HCC-1/HCC-3 Protein - NBP2-34926 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

Recombinant Human CCL14/HCC-1/HCC-3 Protein - NBP2-34925 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

CCL14/HCC-1/HCC-3 Partial Recombinant Protein - H00006358-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL14/HCC-1/HCC-3 Recombinant Protein - H00006358-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL14/HCC-1/HCC-3 Recombinant Protein - P3618 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL14/HCC-1/HCC-3 Protein - NBP1-99402 from Novus Biologicals Category Protein Prices $309.00 Sizes 10 µg Species Human

Recombinant Human CCL14/HCC-1/HCC-3 Protein - NBP1-51007 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CCL14 protein - GTX29846 from GeneTex Category Protein Prices $299.00 Sizes 10 μg Species Human

CCL14 recombinant protein - GTX65243 from GeneTex Category Protein Prices $249.00 Sizes 10 μg Source E. coli Species Human

CCL14 Recombinant Protein (Active) - GTX48371-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

CCL14 Recombinant Protein (Active) - GTX48372-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

Recombinant Human CCL14a/HCC-1 - 324-HC-010 from R&D Systems Category Protein Source E. coli-derived, Thr20-Asn93

Recombinant Human CCL14a/HCC-1 - 324-HC-050 from R&D Systems Category Protein Source E. coli-derived, Thr20-Asn93

Recombinant Human CCL14a/HCC-1, CF - 324-HC-010/CF from R&D Systems Category Protein Source E. coli-derived, Thr20-Asn93

Recombinant Human CCL14a/HCC-1, CF - 324-HC-050/CF from R&D Systems Category Protein Source E. coli-derived, Thr20-Asn93

Recombinant Human CCL14a/HCC-1 (aa 28-93) - 1578-HC-025 from R&D Systems Category Protein Source E. coli-derived, Gly28-Asn93, with an N-terminal Met

Recombinant Human CCL14a/HCC-1 (aa 28-93), CF - 1578-HC-025/CF from R&D Systems Category Protein Source E. coli-derived, Gly28-Asn93, with an N-terminal Met

CCL14 Protein (OPCB00012) - OPCB00012 from Aviva Systems Biology Category Protein Prices $80.00 Sizes 2 µg

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