mTOR signaling pathway



AKT1 - from Human

Gene Symbol AKT1
Entrez Gene 207
Alt Symbol AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Gene Type protein-coding
Description v-akt murine thymoma viral oncogene homolog 1

AKT2 - from Human

Gene Symbol AKT2
Entrez Gene 208
Alt Symbol HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
Gene Type protein-coding
Description v-akt murine thymoma viral oncogene homolog 2

BRAF - from Human

Gene Symbol BRAF
Entrez Gene 673
Alt Symbol B-RAF1, BRAF1, NS7, RAFB1
Gene Type protein-coding
Description B-Raf proto-oncogene, serine/threonine kinase

EIF4B - from Human

Gene Symbol EIF4B
Entrez Gene 1975
Alt Symbol EIF-4B, PRO1843
Gene Type protein-coding
Description eukaryotic translation initiation factor 4B

EIF4E - from Human

Gene Symbol EIF4E
Entrez Gene 1977
Alt Symbol AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F
Gene Type protein-coding
Description eukaryotic translation initiation factor 4E

EIF4EBP1 - from Human

Gene Symbol EIF4EBP1
Entrez Gene 1978
Alt Symbol 4E-BP1, 4EBP1, BP-1, PHAS-I
Gene Type protein-coding
Description eukaryotic translation initiation factor 4E binding protein 1

MTOR - from Human

Gene Symbol MTOR
Entrez Gene 2475
Alt Symbol FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Type protein-coding
Description mechanistic target of rapamycin (serine/threonine kinase)

HIF1A - from Human

Gene Symbol HIF1A
Entrez Gene 3091
Alt Symbol HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
Gene Type protein-coding
Description hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

IGF1 - from Human

Gene Symbol IGF1
Entrez Gene 3479
Alt Symbol IGF-I, IGF1A, IGFI
Gene Type protein-coding
Description insulin-like growth factor 1 (somatomedin C)

IKBKB - from Human

Gene Symbol IKBKB
Entrez Gene 3551
Alt Symbol IKK-beta, IKK2, IKKB, IMD15, NFKBIKB
Gene Type protein-coding
Description inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

INS - from Human

Gene Symbol INS
Entrez Gene 3630
Alt Symbol IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10
Gene Type protein-coding
Description insulin

IRS1 - from Human

Gene Symbol IRS1
Entrez Gene 3667
Alt Symbol HIRS-1
Gene Type protein-coding
Description insulin receptor substrate 1

PDPK1 - from Human

Gene Symbol PDPK1
Entrez Gene 5170
Alt Symbol PDK1, PDPK2, PDPK2P, PRO0461
Gene Type protein-coding
Description 3-phosphoinositide dependent protein kinase 1

PIK3CA - from Human

Gene Symbol PIK3CA
Entrez Gene 5290
Alt Symbol CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Gene Type protein-coding
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PIK3CB - from Human

Gene Symbol PIK3CB
Entrez Gene 5291
Alt Symbol P110BETA, PI3K, PI3KBETA, PIK3C1
Gene Type protein-coding
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

PIK3CD - from Human

Gene Symbol PIK3CD
Entrez Gene 5293
Alt Symbol APDS, IMD14, P110DELTA, PI3K, p110D
Gene Type protein-coding
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

PIK3CG - from Human

Gene Symbol PIK3CG
Entrez Gene 5294
Alt Symbol PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
Gene Type protein-coding
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

PIK3R1 - from Human

Gene Symbol PIK3R1
Entrez Gene 5295
Alt Symbol AGM7, GRB1, IMD36, p85, p85-ALPHA
Gene Type protein-coding
Description phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

PIK3R2 - from Human

Gene Symbol PIK3R2
Entrez Gene 5296
Alt Symbol MPPH, MPPH1, P85B, p85, p85-BETA
Gene Type protein-coding
Description phosphoinositide-3-kinase, regulatory subunit 2 (beta)

PRKAA1 - from Human

Gene Symbol PRKAA1
Entrez Gene 5562
Alt Symbol AMPK, AMPKa1
Gene Type protein-coding
Description protein kinase, AMP-activated, alpha 1 catalytic subunit

PRKAA2 - from Human

Gene Symbol PRKAA2
Entrez Gene 5563
Alt Symbol AMPK, AMPK2, AMPKa2, PRKAA
Gene Type protein-coding
Description protein kinase, AMP-activated, alpha 2 catalytic subunit

PRKCA - from Human

Gene Symbol PRKCA
Entrez Gene 5578
Alt Symbol AAG6, PKC-alpha, PKCA, PRKACA
Gene Type protein-coding
Description protein kinase C, alpha

PRKCB - from Human

Gene Symbol PRKCB
Entrez Gene 5579
Alt Symbol PKC-beta, PKCB, PRKCB1, PRKCB2
Gene Type protein-coding
Description protein kinase C, beta

PRKCG - from Human

Gene Symbol PRKCG
Entrez Gene 5582
Alt Symbol PKC-gamma, PKCC, PKCG, SCA14
Gene Type protein-coding
Description protein kinase C, gamma

MAPK1 - from Human

Gene Symbol MAPK1
Entrez Gene 5594
Alt Symbol ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
Gene Type protein-coding
Description mitogen-activated protein kinase 1
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